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Acromegaly
Definition
Disease: | Acromegaly | ![]() |
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Category: | Genetic Diseases |
Disease Definition:
When the pituitary gland produces too much growth hormone during adulthood, the hormonal disorder acromegaly occurs, which usually affects middle-aged adults and increases the size of the bones, including the hands, feet and face.
Too much growth hormone in children who are still growing can cause a condition called gigantism, in which they have exaggerated bone growth and an abnormal increase in height.
Available treatments for acromegaly can reduce the risk of complications and significantly improve the symptoms, including the enlargement of the features. However, the condition often isn't recognized immediately, because physical changes occur gradually and the condition is quite uncommon. In case it is not treated promptly, it can lead to serious illness and even become life-threatening.
Work Group:
Prepared by: Scientific Section
Symptoms, Causes
Symptoms:
People with this disorder may notice that they no longer can put on rings that used to fit and that their shoe size has progressively increased, because one of the most common signs of acromegaly is enlarged hands and feet. Some of the gradual changes in the shape of the face caused by this condition may include:
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Causes:
A small gland is located at the base of the brain behind the bridge of the nose, called pituitary, which produces a number of hormones. The growth hormone (GH) that plays an important role in managing physical growth is one of those hormones. |
Complications
Complications:
Some of the major health problems and complications that can be caused by the progression of acromegaly include:
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Treatments:
More than one type of treatment may be needed that focuses on reducing the negative effects of the tumor on the pituitary and surrounding tissues, as well as lowering the production of GH.
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Prognosis: Not available |
Samir Moussa M.D.
Dr. Hani Najjar
Yaser Habrawi , F.R.C.S.Ed
Dr. Talal Sabouni
Dr. Faisal Dibsi
Dr. Tahsin Martini
Dr. Samer Al-Jneidy
Dr . Dirar Abboud