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Indications:

Prepubertal cryptorchidism not caused by anatomical obstruction; selected cases of hypogonadotropic hypogonadism (eg, hypogonadism secondary to pituitary deficiency) in men; induction of ovulation in anovulatory, infertile women in whom the cause of anovulation is secondary and not caused by primary ovarian failure and who have been appropriately pretreated with human menotropins.

Contraindications:

Precocious puberty; prostatic carcinoma or other androgen-dependent neoplasm; prior allergic reaction to hCG.

Adverse reactions:

CNS Headache; irritability; restlessness; depression; fatigue. Genitourinary Precocious puberty; gynecomastia. Metabolic Edema. Miscellaneous Pain at injection site.

Interactions:

Laboratory Test Interactions Interference with radioimmunoassay for gonadotropins, particularly luteinizing hormone.

Warnings:

Monitor Ovary overstimulation Monitor women for signs of overstimulation of the ovary (eg, difficulty breathing, severe pelvic pain, nausea, vomiting, weight gain, stomach pain or bloating, diarrhea, infrequent urination) and report to health care provider immediately if noted. Pregnancy Category C . Lactation Undetermined. Children Safety and efficacy in children younger than 4 yr of age not established. Special Risk Patients Because chorionic gonadotropin may cause fluid retention, use with caution in patients with cardiac or renal disease, epilepsy, migraine, or asthma. Exams Ensure that women have had a thorough gynecological and endocrinological evaluation before starting therapy. Ensure that men have had a thorough medical and endocrinological evaluation before starting therapy. Health care provider use Use in conjunction with human menopausal gonadotropins only by health care provider experienced with infertility problems. Precocious puberty May induce precocious puberty in patients treated for cryptorchidism.

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SOLUTION FOR INJECTION

Dosage and Administration

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