Indications:

Reduction of intraocular pressure in patients w/ open angle glaucoma & ocular hypertension who are insufficiently responsive to topical β-blockers or prostaglandin analogues.

Contraindications:

Reactive airway disease including bronchial asthma or history of bronchial asthma, severe COPD. Sinus bradycardia, 2nd or 3rd degree AV block, overt cardiac failure, cardiogenic shock.

Adverse reactions:

Iris hyperpigmentation, eye irritation including stinging, burning & itching, eye pain & other eye disorders.

Interactions:

Oral Ca-blockers, guanethidine, β-blockers, antiarrhythmics, digitalis glycosides, parasympathomimetics, clonidine, antidiabetics.

Warnings:

History of severe cardiac disease, asthma, patients subject to spontaneous hypoglycaemia, diabetes (esp labile diabetes). May mask signs of hyperthyroidism & worsen Prinzmetal’s angina, severe peripheral & central circulatory disorders & hypotension. Pregnancy, lactation.

Form:

SOLUTION FOR INJECTION