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D Epifrin

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Indications:

Ocular hypertension, Open-angle glaucoma

Contraindications:

Hypersensitivity. Patients with narrow angles, since any pupillary dilatation may cause an attack of angle-closure glaucoma.

Adverse reactions:

Ocular hyperaemia, burning, stinging, irritation, follicular conjunctivitis, mydriasis, allergic reactions, adrenochrome deposits in the conjunctiva and cornea, headache, browache and eye pain. Very rarely, tachycardia and hypertension may occur. Potentially Fatal: Generally well tolerated. Side effects fewer when compared to epinephrine drops.

Interactions:

Additive ocular hypotensive effects with other anti-glaucoma drugs.

Warnings:

Aphakic patients; lactation. Pregnancy: Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).

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