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Caduet

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Indications:

Amlodipine is used to treat high blood pressure and angina. Angina is characterized by episodes of crushing chest pain that usually results from a lack of oxygen in the heart muscle due to clogged arteries. Amlodipine is a calcium channel blocker, a type of drug that dilates blood vessels and slows the heart to reduce blood pressure and the pain of angina. Atorvastatin is a cholesterol-lowering drug. Your doctor may prescribe it along with a special diet if your blood cholesterol or triglyceride level is high enough to put you in danger of heart disease, and you have been unable to lower your readings by diet alone. Atorvastatin works by helping to clear harmful low-density lipoprotein (LDL) cholesterol out of the blood and by limiting the body’s ability to form new cholesterol.

Contraindications:

Never take Caduet during pregnancy or while breastfeeding. Avoid Caduet if you have liver disease, or if the drug gives you an allergic reaction.

Adverse reactions:

* Side effects of amlodipine may include: Dizziness, fatigue, flushing, fluid retention and swelling, headache, palpitations (fluttery or throbbing heartbeat) * Side effects of atorvastatin may include: Abdominal pain, constipation, gas, indigestion

Interactions:

Antacids Cimetidine Colestipol Cyclosporine Digoxin Erythromycin Fluconazole Gemfibrozil Itraconazole Ketoconazole Lipitor, which contains atorvastatin Niacin Norvasc, which contains amlodipine Oral contraceptives Spironolactone

Warnings:

There is a slight chance of liver damage from the atorvastatin contained in Caduet. Your doctor may order a blood test to check your liver function before you start taking the drug, again at 12 weeks after you begin therapy or your dosage is increased, and periodically thereafter. If the tests reveal a problem, you may have to stop using the drug. Drugs like atorvastatin, one of the ingredients in Caduet, have occasionally been known to damage muscle tissue. Be sure to tell you doctor immediately if you notice any unexplained muscle tenderness, weakness, or pain, especially if you also have a fever or feel sick.

Form:

Film Coated Tablets

Dosage and Administration

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