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Estradurine

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Indications:

Men: Prostate cancer. Women: CLIMACTERIC failure symptoms.

Contraindications:

active thrombophlebitis or thromboembolic disease progress * hyperlipoproteinemi * severely impaired liver function and / or jaundice * endometrial and ovarian * postmenopausal bleeding * breast cancer in young women It’s also contraindicated in patients with known hypersensitivity to estradiol, mepivacaine or any other ingredients.

Adverse reactions:

Blood and lymphatic system Uncommon: Thrombosis risk at high doses (in men) Endocrine system Common: Gynaecomastia (male) Less common: uterine haemorrhage, tension in the breasts (in women) General disorders and administration site Common: Impotence (in men) Uncommon: edema and Saltretention tendency The following adverse reactions have been reported with estrogen therapy: Cardiac: Heart failure, myocardial infarction Blood and lymphatic system: High blood pressure, thrombophlebitis, thromboembolism Gastrointestinal: Nausea, vomiting Skin and subcutaneous tissue disorders: erythema Endocrine: testicular atrophy Metabolism and nutrition: Reduced glucose tolerance General disorders and administration site conditions: headache, migraine, weight effects, decreased libido Hepatobiliary disorders: Cholelitiasis, cholestatisk jaundice Psychiatric disorders: Changes in mood (elation or depression) After intramuscular administration of Popular urine can damage local injection site occur, as sterile abscess or inflammatory infiltrates. The solution should be shaken well before use and injected deep into a healthy glutealmuskel. Allergic reactions caused by mepivacaine, such as skin reactions, bronchial asthma and anaphylactic shock may occur. Isolated cases of fatal liver toxicity when combined with urine Performing oral estrogen are reported. In men, mild gynecomastia and other feminized symptoms occur in women and in some cases the tension in the breast and uterine occur. Overdose (Read more about overdose) Transient feminization (in men) is the most probable sign of overdose. There is no specific antidote, treatment must be symptomatic.

Interactions:

unavailable

Warnings:

should be discontinued if any of the following occurs: * the occurrence of thrombophlebitis or thromboembolic disease. * sudden onset of decreased vision (risk of obstruction of retinalven) * elevation of blood pressure * migraine * cholestatic hepatitis

Form:

SOLUTION FOR INJECTION

Dosage and Administration

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Consultants Corner

Dr. Tahsin Martini

Dr. Tahsin Martini Degree status: M.D. in Ophthalmology

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