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Ampixin 500

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Indications:

1 - Upper and lower respiratory tract infections, such as otitis tonillitis, bronchitis, throat and nose infections caused by staphylococci, strpto-cocci, diplococcus pneumonia, and H. influenza. 2- Gastrointestinal infection : enterities, typhoid and paratyphoid caused by sheigella, salmonella, escherichia coli, proteus mirabilis and entero-cocci. 3- Urogenital tract infection : Such as urethritis, cystitis, pyelonephritis, prostatitis caused by neisseria gonorrhea, escherichia coli, and proteus miabilis. 4- In skin and soft tissue infection : Such as furunculosis, abcesses, cellu-litis and skin ulcerations, caused mostly by staphylococci. 5- Bone, joint infecttions, and meningitis : Caused by staphylococci and neisseria meningitides, etc. 6- As prophylaxis of bacterial endocarditis or abscess after minor surgery such as tonsillectomy, tooth extraction, as well as those who have changed their heart valves.

Contraindications:

This medicine is not given to individuals who have previous Penicillin or cephalosporin allergy and should be used with caution in individuals with histories of significant allergies and/or asthma.

Adverse reactions:

This medicine is well tolerated, and the side effects - if happened - are less frequent in oral than parenteral AMICLOXAN therapy, and are usually of a mild transitory nature, such as skin eruptions, urticaria, nausea, diarrhea, indigestion, blood dyscraia, joint pains, fever decrease in the number ofneutrophils, increase in the number of eosinophiles but these undesirable symptoms disappear after the discontinuation of treatment.

Interactions:

Concomitant administration of Cephalosporins and Penicillins, or Cephalsporins and aminoglycoside antibiotics, or Cephalosporins and diuretics can produce toxic effects.

Warnings:

Haematological studies as well as liver and renal function tests are advisable in long-term treatment, fungy might grow in some cases . It should be given with caution to patients with allergic nature as it might produce anaphy lactic shock in case of renal insufficiency . In case the dose must be decreased or the interval between the doses prolonged . It should be given with caution to infants with jaundice ; when dermatological reactions appear the drug must be stopped.

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