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Active immunisation of children from 6 weeks of age, adolescents and adults, for the prevention of invasive disease caused by Neisseria meningitidis serogroup C.


Hypersensitivity to any component of the vaccine. Persons who have shown signs of hypersensitivity

Adverse reactions:

Immune System Disorders: Very rare (<0.01%): lymphadenopathy, anaphylaxis, hypersensitivity reactions including bronchospasm, facial oedema and angioedema. Nervous System Disorders: Very rare (<0.01%): dizziness, convulsions including febrile convulsions, faints, hypoaesthesia and paraesthesia, hypotonia. There have been very rare reports of seizures following MENJUGATE® SYRINGE vaccination; individuals have usually rapidly recovered. Some of the reported seizures may have been faints. The reporting rate of seizures was below the background rate of epilepsy in children. In infants seizures were usually associated with fever and were likely to be febrile convulsions. There have been very rare reports of visual disturbances and photophobia following vaccination with Meningococcal group C conjugate vaccines, usually in conjunction with other neurological symptoms like headache and dizziness. Respiratory, thoracic and mediastinal disorders: Apnoea in very premature infants (? 28 weeks of gestation) Gastrointestinal Disorders: Very rare (<0.01%): vomiting, nausea and diarrhoea. Skin and Subcutaneous Tissue Disorders: Very rare (<0.01%): rash, urticaria, pruritus, purpura, erythema multiforme and Stevens-Johnson Syndrome Musculoskeletal, connective tissue and bone disorders: Very rare (<0.01%): myalgia and arthralgia Renal and urinary disorders: Relapse of nephrotic syndrome has been reported in association with Meningococcal group C conjugate vaccines.


must not be mixed with other vaccines in the same syringe. Separate injection sites should be used if more than one vaccine is being administered. Inactivated vaccines and live vaccines, particularly those in the childhood schedule, can be given during the same visit but in different limbs. Administration at the same time as the following vaccines does not reduce the immunological response to any of these other antigens: • Polio (inactivated polio vaccine [IPV] and oral polio vaccine); • Diphtheria (D) and Tetanus (T) toxoids alone or in combination with whole cell or acellular Pertussis (aP); • Haemophilus Influenzae type B (Hib) conjugate vaccine; • Hepatitis B (HBV) vaccine administered alone or at the same time as combined vaccine containing diphtheria, tetanus, Hib, inactivated polio and acellular pertussis; • Combined measles, mumps and rubella; or • 7-valent pneumococcal conjugate vaccine (Prevenar). The effect of concomitant administration of Menjugate with 7-valent pneumococcal conjugate vaccine (Prevenar) and a hexavalent vaccine (DTaP-HBV-IPV-Hib) on immune responses was assessed in infants vaccinated at median ages of approximately 2, 4.5 and 6.5 months. The potential for immune interference has not been assessed at other primary immunisation schedules. Minor variations in GMT antibody titres were observed between studies; however, the clinical significance, if any, of these observations is not established.


intended for intramuscular use only.


Suspension for Injection

Dosage and Administration

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