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Alodorm

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Indications:

It is used as a hypnotic in the short-term management of insomnia and is reported to act in 30 to 60 minutes to produce sleep lasting for 6 to 8 hours. Nitrazepam is used as a hypnotic in the short – term management of Insomnia. Nitrazepam has also been used in epilepsy, notably for infantile spasms. it also is indicated for the treatment of myoclonic seizures.

Contraindications:

Hypersensitivity to Nitrazepam or any component of the formulation . (cross – sensitivity with other benzodiaepines may exist ) Narrow – angle glancoma . Chidren < 6 months of age ( oral ). Chidren < 30 days of age ( parenteral ). Porphyria.

Adverse reactions:

Drowsiness , sedation , muscle weakness , and ataxia are the most frequent adverse effects and less frequent effects include vertigo , headaehe , confusion ,depression , slurred speech or dysarthria , changes in libido , tremor , visual disturbances , urinary rentention or incontinence , gastrointestinal disturbance , changes in salvation and amnesia .

Interactions:

Other drugs that have CNS depressant properties , include Alcohol , antidepressants , antipsychotics , sedative antihistamines , Cimetidine or oral estrogen-containing contraceptives may inhibit the nitro-reduction of nitrazepam, resulting in delayed elimination and prolonged elimination half-life; serum concentrations may also be increased during long-term use.

Warnings:

If Nitrazepam is tobe combined with other psychotropic agents or anticonvulsants or CNS depressants. * After prolonged use , before discontinuing , gradual dosage reduction maybe necessary to avoid the possibility of withdrawal symptoms . *Because Nitrazepam may cause drowsy , dizzy and unsteady , driving and using machines or doing anything else that could be dangerous.

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