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Oral Hygiene Neglect is Fatal

Oral Hygiene Neglect is Fatal

(ePharmaNews) - There is a common belief that the most possible harm of oral-hygiene neglect is tooth decay, but a recent study confirmed that food remnants and saliva stuck on teeth surfaces can be more dangerous, because they form a suitable environment for bacteria growth that can be transmitted by injury to the gums into the bloodstream, which may induce a stroke or a serious heart disease.

A team of researchers discovered that a bacteria that exist in the mouth has the ability to enter the bloodstream, evade the immune system and then access the heart and causes infections in the heart inner lining _endocarditis so-called in medical term_ which is a disease that in most cases requires surgical intervention and causes the death of 30 % of patients.
In addition, there is another disaster these bacteria can cause in the case of entry into bloodstream, as they have the ability to stimulate the production of clots in the blood, which may prevent the blood supply to the heart or brain, causing myocardial infarction and stroke.

Researchers at University of Bristols in collaboration with the Royal College of Surgeons in Ireland (RCSI) has provided an explanation of these blood-clotting properties, as they discovered that these bacteria produce certain proteins on their surfaces similar to those produced naturally within the body to stimulate platelets-gathering, so once they enter the bloodstream, the germs collect platelets around them which protect them of the immune system, and even from antibiotics, making their access to the heart easier, causing both endocarditis and blood-clots.

“Our team has now identified the critical components of the S. gordonii molecule that mimics fibrinogen, so we are getting closer to being able to design new compounds to inhibit it. This would prevent the stimulation of unwanted blood clots,“ said Dr Steve Kerrigan

While Dr. Helen Petersen, who presented this study at the Society for General Microbiology's Spring Conference in Dublin this week, concluded that: “What our work clearly shows is how important it is to keep your mouth healthy through regular brushing and flossing, to keep these bacteria in check”

اضغط هنا للقراءة باللغة العربية

Prepared by: Marcell Shehwaro
Translated by: Marcell Shehwaro

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