Home
My Account
About Us
Forum
Contact us
الواجهة العربية
epharmaweb.com
Medical News Medical News
Aricles Articles
Events Events
Guidelines Guidelines
Videos Library Videos Library
Diseases Diseases
Follow us : facebook twitter Digg Linkedin Boxiz
Newsletter

Please select the categories you are intersted in:
News Articles Guidelines Events Videos Journals' abstracts

Latest Subscribers
Advanced Search »



Heavier Men More Likely to Survive Diffuse Large B-Cell Lymphoma


Heavier Men More Likely to Survive Diffuse Large B-Cell Lymphoma

(epharmanews)- It is well known that being overweight may not be good for one’s health generally, but it appears that overweight men are more likely to survive a particular form of immune system cancer, according to a new study.

The study, published in the Journal of Clinical Oncology, involved 2500 patients of an aggressive form of non-Hodgkin lymphoma called diffuse large B-cell lymphoma (DLBCL).

Lymphoma is a cancer of the lymphocytes, a type of cell that forms part of the immune system. Typically, lymphoma is present as a solid tumor of lymphoid cells. These malignant cells often originate in lymph nodes, presenting as an enlargement of the node (a tumor). It can also affect other organs in which case it is referred to as extranodal lymphoma. Extranodal sites include the skin, brain, bowels and bone.

Non-Hodgkin lymphomas include a large group of cancers that affect the lymphatic system, a part of the immune system, and DLBCL is the most common form.

Earlier studies have linked obesity to a greater risk of developing DLBCL. In certain other cancers - like breast and colon cancers - obese patients might also have a worse prognosis than those who are thinner when they are diagnosed.

"We expected something similar when we started this project," said Kenneth Carson of Washington University School of Medicine in St. Louis, the lead researcher.

The findings were actually very surprising. Men who were obese at diagnosis had only about two-thirds the risk of dying during the study period that normal-weight men had, after considering other factors like age and overall health.

Men who were not obese, but overweight, also had a better prognosis than their normal-weight counterparts, a 27 percent lower death risk during the study period.

The reason why heavier men are more likely to survive DLBCL remains a mystery. Researchers assert that these findings do not mean that men should maintain an obese build, nor should they try to gain more weight. Rather these findings should lead to a better understanding of DLBCL and cancer in general, and to the discovery of effective treatments regardless of gender or weight.

"In my mind, there are two main factors that might explain why overweight and obese patients have improved survival: differences in disease biology, or differences in patient responses to chemotherapy." Carson said.

It is possible that bigger patients are able to tolerate more intense chemotherapy before having severe side effects. But, Carson's team added, other research suggests that obese chemotherapy patients may tend to get lower doses relative to their body size.


اضغط هنا للقراءة باللغة العربية

Prepared by: Marcell Shehwaro


Source :

ePharmaNews






Other Comments

Add a comment

You must sign in to use this servcie

Username:
Password:


facebook comments

Forgot your password


sign up

Consultants Corner

Dr. Hani Najjar

Dr. Hani Najjar Pediatrics, Neurology

Dr. Samer Al-Jneidy

Dr. Samer Al-Jneidy Pediatrician

Dr . Dirar Abboud

Dr . Dirar Abboud Hepatologist – Gastroenterologist

Dr. Tahsin Martini

Dr. Tahsin Martini Degree status: M.D. in Ophthalmology

Samir Moussa M.D.

Samir Moussa M.D. ENT Specialist

Dr. Faisal Dibsi

Dr. Faisal Dibsi Specialist of Otolaryngology - Head and Neck Surgery

Yaser Habrawi , F.R.C.S.Ed

Yaser Habrawi , F.R.C.S.Ed Consultant Ophthalmologist

Dr. Talal Sabouni

Dr. Talal Sabouni UROLOGY AND KIDNEY TRANSPLANT
Poll

Which of the following you are mostly interested in?

Cancer Research
Mental Health
Heart Disease & Diabetes
Sexual Health
Obesity and Healthy Diets
Mother & Child Health

Disclaimer : This site does not endorse or recommend any medical treatment, pharmaceuticals or brand names. More Details